Medication Beliefs in Patients Following Percutaneous Coronary Intervention: A Cross-sectional Study

Prima Agustia Nova, Ching-Huey Chen
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Patients post percutaneous coronary intervention need to take medication for their health. Beliefs about medication influence patients’ adherence in taking their medication regimens. Therefore, the study aimed to identify medication beliefs in patients following percutaneous coronary intervention in Indonesia. This research used a cross-sectional study with the convenience sampling method. A total of 132 adult patients following Percutaneous Coronary Intervention participated in this study. This study used The Beliefs about Medicines Questionnaire to identify patients’ beliefs about medication. The majority of respondents were male (85.6%) with a mean age of 60 years. Beliefs about general overuse were found to be the highest among other categories; specific-necessity, specific concern, and general harm. Elucidating patients’ beliefs about the medication will provide health care providers with a better understanding of patient medication behaviors after percutaneous coronary intervention. Recognition of patients’ beliefs may aid in targeting specific intervention programs to improve patients’ adherence to medication following Percutaneous Coronary Intervention procedure.


Keywords: medication beliefs, percutaneous coronary intervention (PCI)





Keyakinan Pengobatan pada Pasien yang Menjalani Intervensi Coronary Percutaneous: A Cross-Sectional Study. Pasien pasca intervensi koroner perkutan atau percutaneous coronary intervention (PCI) perlu minum obat untuk kesehatannya. Keyakinan terhadap pengobatan berpengaruh pada kepatuhan pasien dalam menjalani rejimen pengobatan. Penelitian ini bertujuan untuk mengidentifikasi keyakinan pengobatan pada pasien yang mengikuti PCI di Indonesia. Penelitian ini menggunakan studi cross-sectional dengan metode convenience sampling. Sebanyak 132 pasien dewasa yang menjalani prosedur PCI berpartisipasi dalam penelitian ini. Penelitian ini menggunakan The Beliefs about Medicines Questionnaire untuk mengidentifikasi keyakinan pasien tentang pengobatan. Mayoritas responden adalah laki-laki (85,6%) dengan usia rata-rata 60 tahun. Keyakinan tentang penggunaan berlebihan secara umum ditemukan sebagai yang tertinggi di antara kategori lainnya yaitu kebutuhan-spesifik, perhatian khusus, dan bahaya umum. Informasi mengenai keyakinan pasien tentang pengobatan akan memberikan pemahaman yang lebih baik bagi penyedia layanan kesehatan tentang perilaku pengobatan pasien setelah prosedur PCI. Pengakuan keyakinan pasien dapat membantu dalam menargetkan program intervensi khusus untuk meningkatkan kepatuhan pasien terhadap pengobatan setelah prosedur PCI.


Kata Kunci: keyakinan pengobatan, percutaneous coronary intervention (PCI)


medication beliefs; percutaneous coronary intervention (PCI)

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Adisa, R., Alutundu, M.B., & Fakeye, T.O. (2009). Factors contributing to oral hypoglycemic medications among ambulatory type 2 diabetes patients in Southwestern Nigeria. Pharmacy Practice, 7(3): 163-169. doi: 10.4321/s1886-36552009000300006.

Aghabekyan, S., Thompson, M.E., & Abrahamyan, L. (2012). Medication noncompliance and patient satisfaction following percutaneous coronary intervention. Journal of Interventional Cardiology, 25(5): 469-475. doi: 10.1111/j.1540-8183.2012.00743.x.

AlHewiti, A. (2014). Adherence to long-term therapies and beliefs about medications. International Journal of Family Medicine, 2014. doi: 10.1155/2014/479596.

Allen, J.K., Fitzgerald, S.T., Swank, R.T., & Becker, D.M. (1990). Functional status after coronary artery bypass grafting and percutaneous transluminal angioplasty. American Journal Cardiology, 65(12): 921-925. doi: 10.1016/0002-9149(90)90926-r.

Austin, M.A., Casan, J.M.L., Baldi, M.A., Meredith, I.T., Hope, S.A. (2009). Beliefs regarding medications influence patients’ adherence to medical therapy one year following percutaneous coronary intervention. Heart, Lung and Circulation. 18(S3): S92.

Australian Institute of Health and Welfare. (2010). Australia’s health 2010. Australia’s health series no. 12. Cat. No. AUS 122. Canberra: AIHW.

Byrne, M., Walsh, J., & Murphy, A. W. (2005). Secondary prevention of coronary heart disease: patient beliefs and health-related behaviour. Journal of psychosomatic research, 58(5): 403-415. doi: 10.1016/j.jpsychores.2004.11.010

Kementerian Kesehatan RI. (2012). Penyakit Tidak Menular. Buletin Jendela Data dan Informasi Kesehatan, 2(2): 1-14.

De la Torre-Hernández, J.M., Alfonso, F., Hernández, F., Elizaga, J., Sanmartin, M., Pinar, E., . . . Mauri, J. (2008). Drug-eluting stent thrombosis: Results from the multicenter spanish registry ESTROFA (Estudio Español sobre Trombosis de stents Farmacoactivos). Journal of the American College of Cardiology, 51(10): 986-990. doi:

Delima, Mihardja, L., & Siswoyo, H. (2009). Prevalensi dan faktor determinan penyakit jantung di Indonesia. Buletin Peneitian Kesehatan, 37(3): 142-159.

DiMatteo, M.R., Haskard, K.B., & Williams, S.L. (2007). Health beliefs, disease severity, and patient adherence: a meta-analysis. Medical care, 45(6): 521-528. doi: 10.1097/MLR.0b013e318032937e

Farooq, V., Gogas, B.D., & Serruys, P.W. (2011). Restenosis: Delineating the numerous causes of drug-eluting stent restenosis. Circulation: Cardiovascular Interventions, 4(2): 195-205. doi: 10.1161/circinterventions.110.959882.

Franzia, E., Piliang, Y.A., & Saidi, A.I. (2005). Rumah gadang as a symbolic representation of Minangkabau ethnic identity. International Journal of Social Science and Humanity, 5(1):44-49. doi: 10.7763/IJSSH.2015.V5.419.

Gatti, M.E., Jacobson, K.L., Gazmararian, J.A., Schmotzer, B., & Kripalani, S. (2009). Relationships between beliefs about medications and adherence. American Journal of Health-System Pharmcy, 66(7): 657-664. doi: 10.2146/ajhp080064.

Grines, C.L., Bonow, R.O., Casey, D.E., Gardner, T.J., Lockhart, P.B., Moliterno, D.J., . . . Whitlow, P. (2007). Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents: A science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions, American College of Surgeons, and American Dental Association, with representation from the American College of Physicians. Circulation, 115(6): 813-818. doi: 10.1161/circulationaha.106.180944.

Guillemin, F., Bombardier, C., & Beaton, D. (1993). Cross-cultural adaptation of health-related quality of life measures: Literature review and proposed guidelines. Journal of Clinical Epidemiology, 46(12): 1417-1432. doi: 10.1016/0895-4356(93)90142-n.

Ho, P.M., Fihn, S.D., Wang, L., Bryson, C.L., Lowy, E., Maynard, C., . . . Rumsfeld, J.S. (2007). Clopidogrel and long-term outcomes after stent implantation for acute coronary syndrome. American Heart Journal, 154(5): 846-851. doi:

Horne, R., & Weinman, J. (1999). Patients' beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. Journal of Psychosomatic Research, 47(6): 555-567. doi:

Horne, R., Weinman, J., & Hankins, M. (1999). The beliefs about medicines questionnaire: The development and evaluation of a new method for assessing the cognitive representation of medication. Psychology & Health, 14(1): 1-24. doi: 10.1080/08870449908407311.

Hughes, C.M. (2004). Medication non-adherence in the elderly; How big is the problem? Drugs & Aging, 21(12): 793-811. doi: 10.2165/00002512-200421120-00004.

Iakovou, I., Schmidt, T., Bonizzoni, E., Ge, L., Sanqiorqi, G.M., Stankovic, G., . . . Colombo, A. (2005). Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. The Journal of the American Medical Association, 293(17): 2126-2130. doi: 10.1001/jama.293.17.2126.

Kato, T. (1982). Matriliny and migration: Evolving Minangkabau traditions in Indonesia. Ithaca: Cornell University Press.

Levine, G.N., Bates, E.R., Blankenship, J.C., Bailey, S.R., Bittl, J.A., Cercek, B., . . . Ting, H.H. (2011). 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention: A report of the American College of Cardiology Foundation/ American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventions. Circulation, 124(23): e574-e651. doi: 10.1161/CIR.0b013e31823ba622.

Mahler, C., Hermann, K., Horne, R., Jank, S., Haefeli, W.E., & Szecsenyi, J. (2010). Patients' beliefs about medicines in a primary care setting in Germany. Journal of Evaluation in Clinical Practice, 18(2): 409-413. doi: 10.1111/j.1365-2753.2010.01589.x.

Ludman, P.F. (2011). British Cardiovascular Intervention Society National Audit of Percutaneous Coronary Interventional Procedures Public Report, Annual Public Report 2011. Retrieved from:

Odell, A., Grip, L., & Hallberg, L.R.M. (2006). Restenosis after percutaneous coronary intervention (PCI): Experiences from the patients' perspective. European Journal of Cardiovascular Nursing, 5(2): 150-157. doi: 10.1016/j.ejcnurse.2005.10.004.

Osterberg, L., & Blaschke, T. (2005). Adherence to medication. New England Journal of Medicine, 353(5): 487-497. doi: 10.1056/NEJMra050100.

Patel, M., Kim, M., Karajgikar, R., Kodali, V., Kaplish, D., Lee, P., . . . Kini, A. S. (2010). Outcomes of patients discharged the same day following percutaneous coronary intervention. Journal of the American College of Cardiology: Cardiovascular Interventions, 3(8): 851-858. doi: 10.1016/j.jcin.2010.05.010.

Phatak, H., & Thomas, J. (2006). Relationships between beliefs about medication and nonadherence to prescribed chronic medications. The Annals of Pharmacotherapy; 40(10): 1737–1742. doi: 10.1345/aph.1H153.

Polit, D.F., & Beck, C.T. (2006). The content validity index: Are you sure you know what's being reported? Critique and recommendations. Research in Nursing & Health, 29(5): 489-497. doi: 10.1002/nur.20147.

Ramakrishnan, S., Mishra, S., Chakraborty, R., Chandra, K.S., & Mardikar, H.M. (2013). The report on the Indian coronary intervention data for the year 2011–National Interventional Council. Indian heart journal, 65(5): 518-521. doi: 10.1016/j.ihj.2013.08.009.

Rolnick, S.J., Pawloski, P.A., Hedblom, B.D., Asche, S.E., & Bruzek, R.J. (2013). Patient characteristics associated with medication adherence. Clinical Medicine & Research, 11(2): 54-65. doi: 10.3121/cmr.2013.1113.

Rushworth, G. F., Cunningham, S., Mort, A., Rudd, I., & Leslie, S. J. (2012). Patient-specific factors relating to medication adherence in a post-percutaneous coronary intervention cohort. International Journal of Pharmacy Practice, 20(4): 226-237. doi: 10.1111/j.2042-7174.2011.00185.x.

Saks E.K., Wiebe, D.J., Cory, L.A., Sammel, M.D., & Arya, L.A. (2012). Beliefs about medications as a predictor of treatment adherence in women with urinary incontinence. Journal of Women’s Health, 21(4): 440-446. doi: 10.1089/jwh.2011.2952.

Schuz, B., Marx, C., Wurm S., Warner, L.M., Ziegelmann, J.P., Schwarzer, R., & Tesch-Romer, C. (2011). Medication beliefs predict medication adherence in older adults with multiple illness. Journal of Psychosomatic Research, 70(2): 179-187. doi: 10.1016/j.jpsychores.2010.07.014.

Steinhubl S.R., Berger, P.B., Mann, J.T 3rd., Fry, E.T., DeLago, A., Wilmer, C., Topol, E.J., CREDO investigators, Clopidogrel for the Reduction of Events During Observtion. (2002). Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: A randomized controlled trial. The Journal of the American Medical Association, 288(19): 2411-2420. doi: 10.1001/jama.288.19.2411.

Sud, A., Kline-Rogers E.M., Eagle, K.A., Fang, J., Armstrong, D.F., Rangarajan, K., … Erickson, S.R. (2005). Adherence to medications by patients after acute coronary syndromes. The Annals of Pharmacotherapy, 39(11): 1792-1797.

Tavakol, M., & Dennick, R. (2011). Making sense of Cronbach's alpha. International Journal of Medical Education, 2011(2): 53-55. doi: 10.5116/ijme.4dfb.8dfd.

Thier, S.L., Yu-Isenberg, K.S., Leas, B.F., Cantrell, C.R., DeBussey, S., Goldfarb, N.I., & Nash, D.B. (2008). In chronic disease, nationwide data show poor adherence by patients to medication and physicians to guidelines. Managed Care, 17(2): 48-52.

Trans, N., Coffman, J.M., Sumino, K., & Cabana, M.D. (2014). Patient reminder systems and asthma medication adherence: A systematic review. Journal of Asthma, 51(5): 536-543. doi: 10.3109/02770903.2014.888572.

Vlachojannis, G.J., Claessen, B.E., & Dangas, G.D. (2012). Early stent trombosis after percutaneous coronary intervention for acute myocardial infarction. Interventional Cardiology, 7(1): 33-36.

Wild, D., Martin, A.G., Eremenco, S., McElroy, S., Verjee-Lorenz, A., & Erikson, P. (2005). Principles of good practice for the translation and cultural adaptation process for Patient-Reported Outcomes (PRO) Measures: Report of the ISPOR task force for translation and cultural adaptation. Value in Health, 8(2): 94-104. doi: 10.1111/j.1524-4733.2005.04054.x.


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